Fatal intrahepatic hemorrhage after nadroparin use for total hip arthroplasty

Low-molecular-weight heparins have become the predominant choice for deep venous thrombosis prophylaxis and treatment. However, their use may cause bleeding complications. Intrahepatic bleeding is exceptional and only very few cases have been described. The authors present a unique case of fatal intrahepatic hematoma complicating nadroparin use in a 65-year-old woman with a hepatic cyst who was admitted to hospital for unilateral total hip arthroplasty. At autopsy, hemoperitoneum (2,000ml of blood and clots) was evident. A ruptured sub-capsular hematoma involving the right lobe of the liver was observed. The hemorrhage within the cyst induced by the nadroparin use was likely responsible for the subsequent hepatic hematoma, liver rupture, and death. This case highlights the need for pathologists and surgeons to be aware of the possibility of intrahepatic hematoma in patients who have received low-molecular-weight heparins, undergone major surgery and present postoperative hemodynamic instability, especially in those with preoperative diagnosis of hepatic cyst

Governing multicultural Brussels: paradoxes of a multi-level, multi-cultural, multi-national urban anomaly

Updating our earlier work on Brussels as the paradigm of a multi-level, multi-cultural, multi-national city, and in the context of Brussels’s recent troubled emergence as the epicentre of violent conflict between radical political Islam and the West, this paper sets out the paradoxical intersection of national (i.e. Flemish and Francophone), non-national and ethnic minority politics in a city placed as a multi-cultural and multi-national ‘urban anomaly’ at the heart of linguistic struggle of the two dominant Belgian communities. Brussels is one of the three Regions of the Belgian federal model alongside Flanders and Wallonia. It is also an extraordinarily diverse and cosmopolitan city, in which a mixed language Belgian population lives alongside very high numbers of resident non-nationals, including European elites, other European immigrant workers, and immigrants from Africa and Asia. After laying out the complex distribution of power and competences within the Belgian federal structure, we explore whether these structures have worked over the years to include or exclude disadvantaged ethnic groups. To better understand these processes, we introduce our view of the multi-level governance perspective

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

In an international cohort of 279 patients with hypoxemic influenza pneumonia, we identified 13 patients (4.6%) with autoantibodies neutralizing IFN-alpha and/or -omega, which were previously reported to underlie 15% cases of life-threatening COVID-19 pneumonia and one third of severe adverse reactions to live-attenuated yellow fever vaccine. Autoantibodies neutralizing type I interferons (IFNs) can underlie critical COVID-19 pneumonia and yellow fever vaccine disease. We report here on 13 patients harboring autoantibodies neutralizing IFN-alpha 2 alone (five patients) or with IFN-omega (eight patients) from a cohort of 279 patients (4.7%) aged 6-73 yr with critical influenza pneumonia. Nine and four patients had antibodies neutralizing high and low concentrations, respectively, of IFN-alpha 2, and six and two patients had antibodies neutralizing high and low concentrations, respectively, of IFN-omega. The patients' autoantibodies increased influenza A virus replication in both A549 cells and reconstituted human airway epithelia. The prevalence of these antibodies was significantly higher than that in the general population for patients 70 yr of age (3.1 vs. 4.4%, P = 0.68). The risk of critical influenza was highest in patients with antibodies neutralizing high concentrations of both IFN-alpha 2 and IFN-omega (OR = 11.7, P = 1.3 x 10(-5)), especially those <70 yr old (OR = 139.9, P = 3.1 x 10(-10)). We also identified 10 patients in additional influenza patient cohorts. Autoantibodies neutralizing type I IFNs account for similar to 5% of cases of life-threatening influenza pneumonia in patients <70 yr old

Les difficultés du consociativisme

The Difflculties of Consociativism. Alessandro Pizzorno [90-112]. From the seventies, Italian politics has been characterized by a fundamental dualism between «¦manifest» politics (ideological oppositions, conflicts between projects of society) and «hidden» politics (consociativism, agreements between government and opposition parties in order to define legislative decisions and share political ressources). The logics of the latter have progessively become more important than those of the former, generalizing a consumerist relationship to politics - for representatives as well as voters. It is certainly in this dualism that one has to look for the main reasons for parties' delegitimization and the institutionnal crisis in contemporary Italy.Les difficultés du consociativisme. Alessandro Pizzorno [90-112]. A partir des années soixante-dix, la vie politique italienne a été caractérisée par un dualisme fondamental entre la politique «manifeste» (oppositions idéologiques, conflits entre des projets de société) et la politique «cachée» (consociativisme, arrangements entre les partis de majorité et les partis d'opposition pour définir les décisions législatives et se partager les ressources publiques). Les logiques de la seconde ont progressivement pris le dessus sur celles de la première, généralisant un rapport consumériste à la politique, tant de la part des élus que des électeurs. C'est certainement dans un tel dualisme qu'il faut rechercher les causes principales de la délégitimation des partis et de la crise des institutions dans l'Italie contemporaine.Pizzorno Alessandro. Les difficultés du consociativisme. In: Politix, vol. 8, n°30, Deuxième trimestre 1995. Incertitudes italiennes, sous la direction de Jean-Louis Briquet , Christophe Bouillaud, Jean-Yves Dormagen et Isabelle Sommier. pp. 91-112

Considérations sur les théories des mouvements sociaux

Pizzorno Alessandro. Considérations sur les théories des mouvements sociaux. In: Politix, vol. 3, n°9, Premier trimestre 1990. En Vert et contre tout ? L'écologie en politique. pp. 74-80

Familismo amorale e marginalità storica ovvero perché non c’è niente da fare a Montegrano (1967)

Banfield’s work does not follow the research model it had previously proposed for the following reasons: 1) the behavior of the people of Montegrano is not reducible to che simple maximization of the material and immediate advantage of the family nucleus.2) the people of Montegrano are not making the least effort to amelionrate their conditions because nothing which they could do would do any better to them. Banfield moreover is conscious of this. 3) The amoral familism does not explain why in Montegrano people live in such conditions that, being in Montegrano, nothing could be done to change things.4) Banfield fails to identify the causes of the situation of Montegrano because in his analysis he assumes Montegrano ad an isolated object. 5) to understand Montegrano it is rather necessary to study the phenomenon of historical marginality, a situation typical of communities like Montegrano